Grape seed proanthocyanidin extract inhibits human esophageal squamous cancerous cell line ECA109.

PMID: Mediators Inflamm. 2018 ;2018:3403972. Epub 2018 Dec 17. PMID: 30647533 Abstract Title: Grape Seed Proanthocyanidin Extract Inhibits Human Esophageal Squamous Cancerous Cell Line ECA109 via the NF-B Signaling Pathway. Abstract: Esophageal squamous cell carcinoma is the most common type of squamous cell carcinoma. Grape seed proanthocyanidin extract (GSPE) is considered to exhibit anticancer activity … Read moreGrape seed proanthocyanidin extract inhibits human esophageal squamous cancerous cell line ECA109.

Artemisia dracunculus administration on glycemic control, insulin sensitivity, and insulin secretion.

PMID: J Med Food. 2016 May ;19(5):481-5. Epub 2016 Apr 20. PMID: 27097076 Abstract Title: Effect of Artemisia dracunculus Administration on Glycemic Control, Insulin Sensitivity, and Insulin Secretion in Patients with Impaired Glucose Tolerance. Abstract: To evaluate the effect of Artemisia dracunculus on glycemic control, insulin sensitivity, and insulin secretion in patients with impaired glucose … Read moreArtemisia dracunculus administration on glycemic control, insulin sensitivity, and insulin secretion.

Protective effects of Withania somnifera extract in a model of amyotrophic lateral sclerosis.

PMID: Exp Neurol. 2018 Nov ;309:193-204. Epub 2018 Aug 19. PMID: 30134145 Abstract Title: Protective effects of Withania somnifera extract in SOD1mouse model of amyotrophic lateral sclerosis. Abstract: Withania somnifera (WS; commonly known as Ashwagandha or Indian ginseng) is a medicinal plant whose extracts have been in use for centuries in various regions of the … Read moreProtective effects of Withania somnifera extract in a model of amyotrophic lateral sclerosis.

Withaferin A attenuates ovalbumin induced airway inflammation.

PMID: Front Biosci (Landmark Ed). 2019 01 1 ;24:576-596. Epub 2019 Jan 1. PMID: 30468675 Abstract Title: Withaferin A attenuates ovalbumin induced airway inflammation. Abstract: The molecular mechanism of how airway inflammation develops is not fully understood. Withaferin A (WA) is a natural phytochemical isolated from the plant. It is a well-investigated bioactive compound that … Read moreWithaferin A attenuates ovalbumin induced airway inflammation.

Cannabinoids may be an effective adjunct for the treatment of pancreatic cancer.

PMID: J Pancreat Cancer. 2019 ;5(1):1-7. Epub 2019 Jan 25. PMID: 30706048 Abstract Title: Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer. Abstract: Cannabinoid extracts may have anticancer properties, which can improve cancer treatment outcomes. The aim of this review is to determine the potentially utility of cannabinoids in the treatment of pancreatic … Read moreCannabinoids may be an effective adjunct for the treatment of pancreatic cancer.

Hesperetin prevents bone resorption by inhibiting RANKL-induced osteoclastogenesis.

PMID: Front Pharmacol. 2018 ;9:1028. Epub 2018 Sep 11. PMID: 30254586 Abstract Title: Hesperetin Prevents Bone Resorption by Inhibiting RANKL-Induced Osteoclastogenesis and Jnk Mediated Irf-3/c-Jun Activation. Abstract: Bone homeostasis and resorption is regulated by the proper activation of osteoclasts, whose stimulation largely depends on the receptor activator of nuclear factorκB ligand (RANKL)-RANK signaling. Herein, for … Read moreHesperetin prevents bone resorption by inhibiting RANKL-induced osteoclastogenesis.

findings indicate that valerian root extract alters functional brain connectivity in relation to anxiety.

PMID: Phytother Res. 2019 Jan 10. Epub 2019 Jan 10. PMID: 30632220 Abstract Title: Valerian extract alters functional brain connectivity: A randomized double-blind placebo-controlled trial. Abstract: Valerian root is the most commonly used herbal supplement for sedation and anxiolysis, but it is unknown whether it may affect functional brain connectivity. Our goal was to use … Read morefindings indicate that valerian root extract alters functional brain connectivity in relation to anxiety.

Effect of fermented Spirulina maxima extract on cognitive-enhancing activities in mice with scopolamine-induced dementia.

PMID: Evid Based Complement Alternat Med. 2018 ;2018:7218504. Epub 2018 Nov 26. PMID: 30598686 Abstract Title: Effect of FermentedExtract on Cognitive-Enhancing Activities in Mice with Scopolamine-Induced Dementia. Abstract: This work provides the first demonstration thatextract fermented with the lactic acid bacteriumHY-08 has the ability to ameliorate scopolamine-induced memory impairment in mice. The fermented extract exhibited … Read moreEffect of fermented Spirulina maxima extract on cognitive-enhancing activities in mice with scopolamine-induced dementia.

Spirulina platensis alone or in combination with vitamin c minimized the nephrotoxic effects of amikacin.

PMID: Environ Sci Pollut Res Int. 2019 Jan 26. Epub 2019 Jan 26. PMID: 30685861 Abstract Title: Influence of Spirulina platensis and ascorbic acid on amikacin-induced nephrotoxicity in rabbits. Abstract: The current study was performed to investigate the nephroprotective efficacy of Spirulina platensis (SP) and the possible benefits of combining SP and ascorbic acid (AA) … Read moreSpirulina platensis alone or in combination with vitamin c minimized the nephrotoxic effects of amikacin.

Zataria multiflora could be suggested for use against asthma.

PMID: Avicenna J Phytomed. 2017 Nov-Dec;7(6):531-541. PMID: 29299436 Abstract Title: The effect ofand carvacrol on wheezing, FEV1 and plasma levels of nitrite in asthmatic patients. Abstract: Objective: The preventive effect ofin animal models of asthma has been reported. In the present study, its effect on wheezing, forced expiratory volume in 1 second, and plasma nitrite … Read moreZataria multiflora could be suggested for use against asthma.

According to the results of studies, oral Z. multiflora essential oil (2%) is a good candidate for management of IBS.

PMID: J Diet Suppl. 2018 Jan 15:1-10. Epub 2018 Jan 15. PMID: 29333891 Abstract Title: Therapeutic Potential of Zataria multiflora Boiss in Treatment of Irritable Bowel Syndrome (IBS). Abstract: Irritable Bowel syndrome (IBS), the most common chronic functional gastrointestinal disorder, is categorized as IBS-C and IBS-D, which are equivalent to Ghoolenj Rihi and Maghs Rihi … Read moreAccording to the results of studies, oral Z. multiflora essential oil (2%) is a good candidate for management of IBS.

Fucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice.

PMID: J Nutr Biochem. 2019 Feb ;64:198-205. Epub 2018 Oct 25. PMID: 30530259 Abstract Title: Fucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice. Abstract: Fucoxanthin (Fx) and its biotransformed fucoxanthinol (FxOH) present strong anti-cancer effects in vitro and in vivo, however, the underlying mechanisms are not well known. We recently … Read moreFucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice.

These findings indicate the potential application of diosgenin for acute lung injury treatment.

PMID: Int Immunopharmacol. 2013 Feb ;15(2):240-5. Epub 2012 Dec 14. PMID: 23246979 Abstract Title: Diosgenin down-regulates NF-κB p65/p50 and p38MAPK pathways and attenuates acute lung injury induced by lipopolysaccharide in mice. Abstract: Diosgenin (Dio), a major active component of steroidal sapogenin of the traditional Chinese herb Dioscorea zingiberensis C.H.Wright, shows various activities including anti-inflammatory, anti-thrombotic … Read moreThese findings indicate the potential application of diosgenin for acute lung injury treatment.

Diosgenin prevented the atherosclerotic disease progression and concomitant suppression of inflammatory mediators in liver and brain.

PMID: Life Sci. 2018 Mar 1 ;196:28-37. Epub 2018 Jan 13. PMID: 29339101 Abstract Title: Atherogenic diet induced lipid accumulation induced NFκB level in heart, liver and brain of Wistar rat and diosgenin as an anti-inflammatory agent. Abstract: Atherogenic Diet (AD) was given to rats to understand the key role of inflammatory mediators in atherosclerotic … Read moreDiosgenin prevented the atherosclerotic disease progression and concomitant suppression of inflammatory mediators in liver and brain.

Diosgenin protects rats from myocardial inflammatory injury induced by ischemia-reperfusion.

PMID: Med Sci Monit. 2018 Jan 12 ;24:246-253. Epub 2018 Jan 12. PMID: 29329279 Abstract Title: Diosgenin Protects Rats from Myocardial Inflammatory Injury Induced by Ischemia-Reperfusion. Abstract: BACKGROUND Diosgenin, a phytosteroid sapogenin, has anti-inflammatory properties shown to reduce myocardial ischemia-reperfusion injury (MIRI). However, the specific mechanism by which this is achieved is not clear. This … Read moreDiosgenin protects rats from myocardial inflammatory injury induced by ischemia-reperfusion.

Kefir protective effects against nicotine cessation-induced anxiety and cognition impairments.

PMID: Adv Biomed Res. 2014 ;3:251. Epub 2014 Dec 6. PMID: 25590029 Abstract Title: Kefir protective effects against nicotine cessation-induced anxiety and cognition impairments in rats. Abstract: BACKGROUND: Nicotine as one of the potent psychostimulant drugs is characterized by its parasympathomimetic activity. Upon the abrupt discontinuation of nicotine intake, a number of symptoms such as … Read moreKefir protective effects against nicotine cessation-induced anxiety and cognition impairments.

Kefir-derived Lactobacillus extracellular vesicles can be potentially used for developing innovative strategies for alleviating inflammatory bowel disease.

PMID: J Dairy Sci. 2018 Oct ;101(10):8662-8671. Epub 2018 Aug 9. PMID: 30100498 Abstract Title: Therapeutic effects of kefir grain Lactobacillus-derived extracellular vesicles in mice with 2,4,6-trinitrobenzene sulfonic acid-induced inflammatory bowel disease. Abstract: Kefir is a fermented product from yeast and lactic acid bacteria, and has been associated with various health benefits including relieving inflammatory … Read moreKefir-derived Lactobacillus extracellular vesicles can be potentially used for developing innovative strategies for alleviating inflammatory bowel disease.

Lactobacillus brevisCD2 may delay gingivitis development in this model by downregulating an inflammatory cascade.

This post was originally published on this sitePMID:  Oral Dis. 2015 Sep ;21(6):705-12. Epub 2015 Apr 20. PMID: 25720615 Abstract Title:  Modulation of the host response by probiotic Lactobacillus brevis CD2 in experimental gingivitis. Abstract:  OBJECTIVE: Probiotic Lactobacillus brevisCD2 (CD2) exerts anti-inflammatory properties by preventing nitric oxide synthesis. It is hypothesized that oral application of … Read moreLactobacillus brevisCD2 may delay gingivitis development in this model by downregulating an inflammatory cascade.

The results of this study indicated that taking probiotic supplements for 8 weeks among patients with rheumatoid arthritis had beneficial effects.

PMID: Int J Rheum Dis. 2016 Sep ;19(9):869-79. Epub 2016 May 2. PMID: 27135916 Abstract Title: Clinical and metabolic response to probiotic supplementation in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial. Abstract: OBJECTIVE: This study was performed to determine the effects of probiotic supplementation on clinical and metabolic status of patients with rheumatoid … Read moreThe results of this study indicated that taking probiotic supplements for 8 weeks among patients with rheumatoid arthritis had beneficial effects.

These findings confirm that lactobacilli decrease cry and fuss time and provide a dietary support in exclusively breastfed infants with colic.

PMID: Nutrients. 2018 Dec 13 ;10(12). Epub 2018 Dec 13. PMID: 30551654 Abstract Title: Role of Lactobacillus rhamnosus (FloraActive™) 19070-2 and Lactobacillus reuteri (FloraActive™) 12246 in Infant Colic: A Randomized Dietary Study. Abstract: Infant colic is a common condition of unknown pathogenesis that brings frustration to families seeking for effective management. Accumulating evidence suggests that … Read moreThese findings confirm that lactobacilli decrease cry and fuss time and provide a dietary support in exclusively breastfed infants with colic.

L. paracasei SD1 may help to decrease the risk of dental caries.

PMID: Clin Oral Investig. 2014 Apr ;18(3):857-62. Epub 2013 Jul 28. PMID: 23892501 Abstract Title: Lactobacillus paracasei SD1, a novel probiotic, reduces mutans streptococci in human volunteers: a randomized placebo-controlled trial. Abstract: OBJECTIVES: The present study investigates the effect of an oral Lactobacillus paracasei SD1 isolate on a number of salivary mutans streptococci, lactobacilli, and … Read moreL. paracasei SD1 may help to decrease the risk of dental caries.

Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcystosine loss in renal cell carcinoma.

PMID: J Clin Invest. 2019 Jan 31. Epub 2019 Jan 31. PMID: 30702441 Abstract Title: Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcystosine loss in renal cell carcinoma. Abstract: Although ccRCC has been shown to have widespread aberrant cytosine methylation and loss of hydroxymethylation (5hmC), the prognostic impact and therapeutic targeting of this epigenetic aberrancy has … Read moreAscorbic acid-induced TET activation mitigates adverse hydroxymethylcystosine loss in renal cell carcinoma.

Curcumin was significantly more effective than 5-FU in all three cell lines.

PMID: Anticancer Agents Med Chem. 2019 Jan 16. Epub 2019 Jan 16. PMID: 30652650 Abstract Title: Tetrahydrocurcumin, Curcumin, and 5-Fluorouracil Effects on Human Esophageal Carcinoma Cells. Abstract: BACKGROUND: Esophageal cancer responds poorly to traditional therapies, and novel treatments are needed. The phytochemical curcumin is a potential treatment for esophageal squamous cell carcinoma (ESCC). A curcumin … Read moreCurcumin was significantly more effective than 5-FU in all three cell lines.

Protection with thymoquinone against formaldehyde-induced neurotoxicity in the rats.

PMID: Bratisl Lek Listy. 2018 ;119(11):726-730. PMID: 30686007 Abstract Title: Protection with thymoquinone against formaldehyde-induced neurotoxicity in the rats. Abstract: INTRODUCTION: This study aimed to investigate the neurotoxic damage of formaldehyde (FA), which is commonly used in medicine and industrial fields, for the hippocampus of rats and the protective role of thymoquinone (TQ) against this neurotoxicity.METHODS: … Read moreProtection with thymoquinone against formaldehyde-induced neurotoxicity in the rats.

Bergamot fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.

PMID: BMC Biochem. 2011 Apr 15 ;12:15. Epub 2011 Apr 15. PMID: 21496221 Abstract Title: Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines. Abstract: BACKGROUND: Cystic fibrosis (CF) airway pathology is a fatal, autosomal, recessive genetic disease characterized by extensive lung … Read moreBergamot fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.

Anti-infective potential of Citrus bergamia Risso.

PMID: Phytother Res. 2016 Sep ;30(9):1404-11. Epub 2016 May 24. PMID: 27218799 Abstract Title: Anti-infective potential of Citrus bergamia Risso et Poiteau (bergamot) derivatives: a systematic review. Abstract: Infectious diseases remain among the leading causes of morbidity and mortality worldwide, mainly because of the increase of resistance to chemotherapeutic drugs. Nature is the major source … Read moreAnti-infective potential of Citrus bergamia Risso.

LDL-cholesterol lowering effect of a new dietary supplement.

PMID: Lipids Health Dis. 2018 May 24 ;17(1):124. Epub 2018 May 24. PMID: 29793488 Abstract Title: LDL-cholesterol lowering effect of a new dietary supplement: an open label, controlled, randomized, cross-over clinical trial in patients with mild-to-moderate hypercholesterolemia. Abstract: BACKGROUND: Hypercholesterolemia is a major risk factor for cardiovascular disorders and requires specific intervention through an adequate … Read moreLDL-cholesterol lowering effect of a new dietary supplement.

A systematic review of the efficacy of ergogenic aids for improving running performance.

PMID: J Strength Cond Res. 2013 Jun ;27(6):1699-707. PMID: 22890496 Abstract Title: A systematic review of the efficacy of ergogenic aids for improving running performance. Abstract: Running is a common form of activity worldwide, and participants range from”weekend warriors”to Olympians. Unfortunately, few studies have examined efficacy of various ergogenic aids in runners because the majority … Read moreA systematic review of the efficacy of ergogenic aids for improving running performance.

Lemon verbena extract has been shown to be a safe and well-tolerated natural sports ingredient, by reducing muscle damage after exhaustive exercise.

PMID: J Int Soc Sports Nutr. 2018 ;15:5. Epub 2018 Jan 23. PMID: 29410606 Abstract Title: Effects of lemon verbena extract (Recoverben®) supplementation on muscle strength and recovery after exhaustive exercise: a randomized, placebo-controlled trial. Abstract: Background: Exhaustive exercise causes muscle damage accompanied by oxidative stress and inflammation leading to muscle fatigue and muscle soreness. … Read moreLemon verbena extract has been shown to be a safe and well-tolerated natural sports ingredient, by reducing muscle damage after exhaustive exercise.

Chrysanthemum indicum might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseases

PMID: J Ethnopharmacol. 2019 Jan 2. Epub 2019 Jan 2. PMID: 30610932 Abstract Title: Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Chrysanthemum indicum Linne (C. indicum), a healthy food and folk … Read moreChrysanthemum indicum might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseases