PMID: Fitoterapia. 2018 Oct ;130:61-65. Epub 2018 Aug 16. PMID: 30121232 Abstract Title: Anti-inflammatory constituents from Perilla frutescens on lipopolysaccharide-stimulated RAW264.7 cells. Abstract: Perilla frutescens (L.) Britt. (Lamiaceae) is a traditionally medicinal herb in East Asian countries to treat various diseases. In present study, the low-polarity constituents of the aerial parts of P. frutescens were … Read moreAnti-inflammatory constituents from Perilla frutescens on lipopolysaccharide-stimulated RAW264.7 cells.
PMID: J Educ Health Promot. 2018 ;7:147. Epub 2018 Nov 27. PMID: 30596119 Abstract Title: Hepatoprotective effects ofleaf extract on carbon tetrachloride-induced hepatotoxicity in rats. Abstract: INTRODUCTION: Hepatic sickness is a serious problem for human health. The researchers are interested in using medicinal plants including barberry to cure many of these sicknesses. In this study, … Read moreUsing the appropriate dose of B. vulgaris leaf extract can help the improvement of laboratory symptoms of fatty liver.
PMID: Food Funct. 2019 Mar 25. Epub 2019 Mar 25. PMID: 30907897 Abstract Title: Six types of tea reduce high-fat-diet-induced fat accumulation in mice by increasing lipid metabolism and suppressing inflammation. Abstract: A high-fat diet results in obesity because of white fat accumulation. Although tea extracts alleviate lipid metabolism disorders and decrease white fat accumulation, … Read moreTea is a potent anti-obesity agent.
PMID: Molecules. 2019 Feb 12 ;24(3). Epub 2019 Feb 12. PMID: 30759826 Abstract Title: Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung Cancer. Abstract: Non-small cell lung cancer (NSCLC) patients carrying an epidermal growth factor receptor (EGFR) mutation are initially sensitive to EGFR-tyrosine kinase … Read moreCucurbitacin B may be a new candidate for the treatment of gefitinib-resistant non-small cell lung cancer.
PMID: Acta Trop. 2019 Mar 25. Epub 2019 Mar 25. PMID: 30922800 Abstract Title: The electronic song”Scary Monsters and Nice Sprites”reduces host attack and mating success in the dengue vector Aedes aegypti. Abstract: Sound and its reception are crucial for reproduction, survival, and population maintenance of many animals. In insects, low-frequency vibrations facilitate sexual interactions, … Read moreMusic could be developed into a protective and control measure against Aedes-borne diseases.
PMID: Nutr Res. 2019 Feb ;62:13-22. Epub 2018 Nov 17. PMID: 30803503 Abstract Title: Freeze-dried bilberry (Vaccinium myrtillus) dietary supplement improves walking distance and lipids after myocardial infarction: an open-label randomized clinical trial. Abstract: Bilberries, Vaccinium myrtillus, have a high content of phenolic compounds including anthocyanins, which could provide cardiometabolic health benefits following acute myocardial … Read moreFindings in the present study suggest that bilberries may have clinically relevant beneficial effects following acute myocardial infarction.
PMID: Nutrients. 2018 Oct 15 ;10(10). Epub 2018 Oct 15. PMID: 30326572 Abstract Title: Suppressive Effect of theα-Amylase Inhibitor Albumin from Buckwheat (Moench) on Postprandial Hyperglycaemia. Abstract: Inhibiting starch hydrolysis into sugar could reduce postprandial blood glucose elevation and contribute to diabetes prevention. Here, both buckwheat and wheat albumin that inhibited mammalianα-amylase in vitro suppressed … Read moreSuppressive effect of the α-amylase ihibitor albumin from buckwheat.
PMID: J Food Drug Anal. 2019 Jan ;27(1):231-239. Epub 2018 May 26. PMID: 30648576 Abstract Title: A steroidal derivative from Trigonella foenum graecum L. that induces apoptosis in vitro and in vivo. Abstract: Trigonella foenum graecum L. is a dietary herb used in traditional medicine system. In this study, we investigated the cytotoxicity, antitumor, antimetastatic and antiangiogenic … Read moreA steroidal derivative from Trigonella foenum graecum L. that induces apoptosis in vitro and in vivo.
PMID: Eur J Pharmacol. 2019 Feb 15 ;845:24-31. Epub 2018 Dec 28. PMID: 30597130 Abstract Title: Silibinin ameliorates diabetic nephropathy via improving diabetic condition in the mice. Abstract: Diabetic nephropathy (DN) is a major cause of end-stage renal disease and one of the most severe diabetic complications. However, there is lack of effective treatments for … Read moreSilibinin ameliorates diabetic nephropathy via improving diabetic condition in the mice.
PMID: Endocrinology. 2019 Mar 20. Epub 2019 Mar 20. PMID: 30892605 Abstract Title: Chronic Exposure of Mice to Bisphenol-A Alters Uterine FGF Signaling and Leads to Aberrant Epithelial Proliferation. Abstract: Uterine epithelial proliferation is regulated in a paracrine manner by a complex interplay between estrogen (E) and progesterone (P) signaling, wherein E stimulates proliferation and … Read moreChronic exposure to BPA impairs steroid hormone signalling in the mouse uterus, and may contribute to the pathogenesis of uterine hyperplasia and cancer.
This post was originally published on this sitePMID: J Cancer Res Ther. 2019 Jan-Mar;15(1):68-74. PMID: 30880757 Abstract Title: Investigation of apoptotic effect of juglone on CCL-228-SW 480 colon cancer cell line. Abstract: Background: Colon cancer is a major cause of morbidity and mortality in the world. Juglone is a natural compound which has been isolated … Read moreInvestigation of apoptotic effect of juglone on CCL-228-SW 480 colon cancer cell line.
PMID: Antiviral Res. 2019 Apr ;164:1-11. Epub 2019 Jan 31. PMID: 30711418 Abstract Title: Aesculus hippocastanum L. seed extract shows virucidal and antiviral activities against respiratory syncytial virus (RSV) and reduces lung inflammation in vivo. Abstract: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease and bronchiolitis in children worldwide. No … Read moreHorse chestnut. seed extract shows virucidal and antiviral activities against respiratory syncytial virus
PMID: Chin Med. 2019 ;14:7. Epub 2019 Mar 12. PMID: 30911326 Abstract Title: Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells in a P-gp-independent manner through enhanced ROS generation. Abstract: Background: Shikonin (SKN), a naphthoquinone compound, is isolated from Chinese herbal medicineroot and has been studied as an anticancer drug … Read moreCombination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells.
PMID: J Ethnopharmacol. 2019 Apr 24 ;234:106-111. Epub 2019 Jan 11. PMID: 30639231 Abstract Title: Standardized Nigella sativa seed oil ameliorates hepatic steatosis, aminotransferase and lipid levels in non-alcoholic fatty liver disease: A randomized, double-blind and placebo-controlled clinical trial. Abstract: ETHNOPHARMACOLOGICAL EVIDENCE: Nigella sativa (N. sativa) seeds are used in the Iranian traditional medicine for … Read moreN. sativa seed oil seems to be safe and improve liver steatosis and injury and blood levels of triglycerides, LDL-C and HDL-C in the NAFLD patients.
PMID: Front Cell Infect Microbiol. 2018 ;8:372. Epub 2018 Oct 23. PMID: 30406046 Abstract Title: Supplementation With 2′-FL and scGOS/lcFOS Ameliorates Rotavirus-Induced Diarrhea in Suckling Rats. Abstract: Rotavirus (RV) is considered to be the most common cause of gastroenteritis among infants aged less than 5 years old. Human milk bioactive compounds have the ability to … Read moreSupplementation with 2′-FL and scGOS/lcFOS ameliorates rotavirus-induced diarrhea.
PMID: Pediatr Diabetes. 2018 12 ;19(8):1400-1406. Epub 2018 Sep 25. PMID: 30136344 Abstract Title: Prospects for primary prevention of type 1 diabetes by restoring a disappearing microbe. Abstract: Prevention of childhood-onset type 1 diabetes has become more urgent with its marked increased incidence in recent decades in the modern world. Temporally associated with the rising … Read moreProspects for primary prevention of type 1 diabetes by restoring a disappearing microbe.
PMID: Microb Pathog. 2018 Dec ;125:454-462. Epub 2018 Oct 11. PMID: 30316007 Abstract Title: Evaluation of anti-diabetic attributes of Lactobacillus rhamnosus MTCC: 5957, Lactobacillus rhamnosus MTCC: 5897 and Lactobacillus fermentum MTCC: 5898 in streptozotocin induced diabetic rats. Abstract: Interest in probiotics has grown significantly in the last decades due to their reported nutritional and health … Read moreDaily consumption of probiotic fermented milk can be effective in combating of type 1 diabetes and its complications.
PMID: Cell Mol Biol (Noisy-le-grand). 2019 Jan 31 ;65(1):1-7. Epub 2019 Jan 31. PMID: 30782287 Abstract Title: Ameliorative effect of probiotics (Lactobacillus paracaseii and Protexin®) and prebiotics (propolis and bee pollen) on clindamycin and propionic acid-induced oxidative stress and altered gut microbiota in a rodent model of autism. Abstract: Colonization by toxin-producing bacteria in the … Read morePro-and prebiotic supplements may be effective to revive healthy digestive system function in autistic patients.
PMID: Food Funct. 2018 Sep 19 ;9(9):4763-4770. PMID: 30113051 Abstract Title: Metabolic and genetic response to probiotics supplementation in patients with diabetic nephropathy: a randomized, double-blind, placebo-controlled trial. Abstract: This study was carried out to evaluate the effects of probiotics administration on the metabolic and genetic profiles in patients with diabetic nephropathy (DN). This was … Read moreProbiotics supplementation had beneficial effects on glycemic control and markers of cardio-metabolic risk.
PMID: Evid Based Complement Alternat Med. 2015 ;2015:153684. Epub 2015 Dec 22. PMID: 26858770 Abstract Title: Germinated Brown Rice Alters Aβ(1-42) Aggregation and Modulates Alzheimer’s Disease-Related Genes in Differentiated Human SH-SY5Y Cells. Abstract: The pathogenesis of Alzheimer’s disease involves complex etiological factors, of which the deposition of beta-amyloid (Aβ) protein and oxidative stress have been … Read moreGerminated brown rice alters Aβ(1-42) aggregation and modulates Alzheimer’s disease-related genes.
PMID: Adv Pharmacol Sci. 2019 ;2019:7581318. Epub 2019 Jan 29. PMID: 30838042 Abstract Title: Antimutagenic and Synergistic Cytotoxic Effect of Cisplatin and Honey Bee Venom on 4T1 Invasive Mammary Carcinoma Cell Line. Abstract: Introduction: Honey bee venom (HBV) has various biological activities such as the inhibitory effect on several types of cancer. Cisplatin is an … Read moreHoney bee venom and cisplatin could cause cell death in a dose-dependent manner.
PMID: J Gynecol Obstet Hum Reprod. 2019 Mar 18. Epub 2019 Mar 18. PMID: 30898624 Abstract Title: Is there a relationship between serum vitamin D with dysmenorrhea pain in young women? Abstract: Dysmenorrhea, also known as painful periods, or menstrual cramps, is pain during menstruation. This study was done in young women that assess the … Read moreSupplementation with vitamin D may be useful to girls for decreasing of dysmenorrhea pain.
n/a PMID: Am J Clin Nutr. 1985 Oct ;42(4):639-43. PMID: 2413754 Abstract Title: Serotonin content of foods: effect on urinary excretion of 5-hydroxyindoleacetic acid. Abstract: Using a highly specific radioenzymatic assay we determined the serotonin concentration in 80 types of foods. The following fruits had a high serotonin concentration (mean +/- SEM) expressed in micrograms/g … Read moreSeveral foods, including plantain, pineapple, banana, Kiwi fruit, plums and tomatoes contains serotonin enhancing properties.
PMID: Crit Rev Food Sci Nutr. 2019 Jan 13:1-14. Epub 2019 Jan 13. PMID: 30638035 Abstract Title: The inhibitory effects of flavonoids onα-amylase and α-glucosidase. Abstract: The objective of this review is to summarize knowledge on the inhibitory effects (IEs) of flavonoids onα-amylase (αA) and α-glucosidase (αG) relevant to the search of substitutes of acarbose … Read moreThe inhibitory effects of flavonoids on α-amylase and α-glucosidase.
PMID: Int J Mol Sci. 2019 Jan 31 ;20(3). Epub 2019 Jan 31. PMID: 30708965 Abstract Title: α-Lipoic Acid Reduces Iron-induced Toxicity and Oxidative Stress in a Model of Iron Overload. Abstract: Iron toxicity is associated with organ injury and has been reported in various clinical conditions, such as hemochromatosis, thalassemia major, and myelodysplastic syndromes. … Read moreAlpha-lipoic acid possesses excellent iron chelating properties.
PMID: J Agric Food Chem. 2019 Mar 20. Epub 2019 Mar 20. PMID: 30892882 Abstract Title: Preventive Efficiency of Green Tea and Its Components on Non-alcoholic Fatty Liver Disease. Abstract: Non-alcoholic fatty liver disease (NAFLD) is a typical chronic liver disease highly correlated with metabolic syndrome. Growing prevalence of NAFLD is supposed to be linked … Read moreAvailable evidences suggested that tea consumption is promising to prevent NAFLD.
PMID: J Clin Pharm Ther. 2019 Feb ;44(1):115-118. Epub 2018 Oct 8. PMID: 30296343 Abstract Title: Fluoxetine-induced Stevens-Johnson syndrome and liver injury. Abstract: WHAT IS KNOWN AND OBJECTIVE: Drug-induced liver injuries (DILI) are overall rare and often associated with use of medications. Medications are also the most common aetiology of Stevens-Johnson syndrome (SJS), but SJS … Read moreA case report of fluoxetine-induced Stevens-Johnson syndrome and liver injury.
PMID: Avicenna J Phytomed. 2019 Jan-Feb;9(1):10-20. PMID: 30788274 Abstract Title: Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis. Abstract: Objective: We aimed to conduct a systematic review and meta-analysis of clinical trials that examined the effects of L-citrulline supplementation on blood pressure (BP).Materials and Methods: We searched MEDLINE, SCOPUS, PUBMED and … Read moreL-citrulline supplementation may reduce systolic blood pressure.
PMID: Adv Clin Exp Med. 2019 Feb ;28(2):171-178. PMID: 30303312 Abstract Title: Effects of puerarin on spatial learning and memory function in mice with acute alcohol consumption: An evaluation based upon firing rate and oxygen saturation analysis. Abstract: BACKGROUND: Ethanol is associated with various medical comorbidities affecting the brain and central nervous system.OBJECTIVES: The use … Read morePuerarin could be of use in treating alcohol-induced memory disorders.
PMID: Iran J Basic Med Sci. 2019 Feb ;22(2):187-196. PMID: 30834085 Abstract Title: Methanolic leaf extract ofattenuates ischemia-reperfusion brain injury in Wistar rats: Potential antioxidant and anti-inflammatory mechanisms. Abstract: Objectives: This study was conducted to evaluate the cerebroprotective effect of methanolic leaf extract of(MePG) in Wistar rats.Materials and Methods: The MePG was initially assessed forantioxidant … Read moreThese findings suggest that the methanolic leaf extract of Punica granatum possesses significant cerebroprotective activity.